Hyocine Butylbromide (Buscopan)

CAS NO: 149-64-4
Batch Molecular FormulaC21H30NO4+
Batch Molecular Weight360.46 g/mol
Physical AppearanceWhite to off white Solid
Melting point139-141
StorageStore at RT
Batch Molecular Structure

Hyoscine butylbromide, commonly sold under the brand name Buscopan, is a medication used to relieve muscle spasms and cramps, particularly in the gastrointestinal (GI) tract. It belongs to a class of drugs known as antispasmodics or anticholinergics. Here are some key points about Buscopan:

  1. Indications: Buscopan is primarily prescribed for the relief of abdominal pain, cramps, and discomfort associated with conditions like irritable bowel syndrome (IBS), functional bowel disorders, and other gastrointestinal issues. It can help relax and relieve spasms in the muscles of the digestive tract, which can reduce pain and discomfort.
  2. Mechanism of Action: The active ingredient in Buscopan, hyoscine butylbromide, acts by blocking certain nerve signals in the GI tract, which leads to muscle relaxation. This can help alleviate the symptoms of abdominal cramping and pain.
  3. Dosage: Buscopan is typically available in the form of tablets and injectable solutions. The dosage and administration instructions will vary depending on the condition being treated, so it’s essential to follow the guidance of a healthcare professional.
  4. Side Effects: Like any medication, Buscopan can have potential side effects. Common side effects may include dry mouth, blurred vision, dizziness, and constipation. It’s crucial to inform your healthcare provider if you experience any severe or unusual side effects.
  5. Contraindications: Buscopan should be used with caution in individuals with certain medical conditions, such as glaucoma, myasthenia gravis, or a history of allergic reactions to hyoscine. It may also interact with other medications, so be sure to inform your healthcare provider of all the drugs you are taking.
  6. Pregnancy and Lactation: If you are pregnant or breastfeeding, it’s important to discuss the use of Buscopan with your healthcare provider, as its safety during these periods is not well established.

Buscopan is widely used to provide relief from gastrointestinal cramps and spasms. However, it should only be used under the guidance of a healthcare professional who can determine the appropriate dosage and duration of treatment based on your specific condition and medical history. If you have any questions or concerns about the use of Buscopan, it is best to consult with your healthcare provider.


  • Hyoscine butylbromide is an antispasmodic medicine which is taken to relieve cramps in the stomach, intestines or bladder. In particular, it helps to ease bloating and the spasm-type pain that can be associated with irritable bowel syndrome and diverticular disease.