Pseudoephedrine HCL

CAS NO: 345-78-8
Batch Molecular FormulaC10H16ClNO • HCl
Batch Molecular Weight201.69
Physical AppearanceWhite Crystalline Powder
SolubilityVery Soluble in Water
StorageStore at RT
Batch Molecular Structure

Pseudoephedrine hydrochloride (Pseudoephedrine HCl) is a decongestant medication commonly used to relieve nasal and sinus congestion associated with various conditions, including the common cold, allergies, and sinusitis. It is available in over-the-counter (OTC) and prescription formulations, often in combination with other medications to provide relief from cold and allergy symptoms. Here are some key points about pseudoephedrine HCl:

  1. Mechanism of Action: Pseudoephedrine works by constricting blood vessels in the nasal passages and sinuses. This action reduces swelling and congestion, allowing for improved airflow and relief from symptoms like a stuffy or runny nose.
  2. Indications: Pseudoephedrine is typically used to alleviate symptoms associated with nasal and sinus congestion, such as congestion, stuffy or runny nose, and sinus pressure. It is not intended to treat the underlying cause of these symptoms but rather to provide temporary relief.
  3. Availability: Pseudoephedrine is available as an over-the-counter medication in many countries, although its sale may be restricted due to concerns about its use in the illegal manufacture of methamphetamine. In some places, it may be sold behind the pharmacy counter or require identification and limits on purchase quantities.
  4. Side Effects: Common side effects of pseudoephedrine may include nervousness, restlessness, increased heart rate, increased blood pressure, and insomnia. It may also cause dizziness, headache, and gastrointestinal upset in some individuals.
  5. Contraindications: Pseudoephedrine is generally not recommended for individuals with certain medical conditions, such as severe hypertension, heart disease, or thyroid disorders. It may interact with certain medications, so it’s important to consult with a healthcare provider or pharmacist before using it, especially if you are taking other medications.
  6. Pregnancy and Lactation: The safety of pseudoephedrine during pregnancy and breastfeeding is not well established. It is generally recommended to use it with caution during pregnancy and consult a healthcare provider before use while breastfeeding.
  7. Misuse and Legal Regulation: Pseudoephedrine is regulated in many places due to its potential use in the illegal production of methamphetamine. There are restrictions on the quantity of pseudoephedrine-containing products that individuals can purchase, and sales may be recorded.

If you plan to use pseudoephedrine or any medication containing pseudoephedrine, it’s important to follow the dosing instructions on the product label and consult a healthcare provider or pharmacist if you have any questions or concerns, particularly if you have preexisting medical conditions or are taking other medications. Misuse or excessive use of pseudoephedrine can lead to adverse effects, including increased heart rate and blood pressure, so it should be used as directed.


  • Nasal congestion
  • Sinus congestion
  • Eustachian tube congestion.